The Hybrid Capture II test detects which groups?

The Hybrid Capture II test detects which groups?

• A. High risk groups for cervical cancer
• B. High risk and low groups for cervical cancer
• C. HPV high risk and low risk types, C. trachomatis and N. gonorrhoeae
• D. High risk HPV types only

Answer: (B)

Hybrid Capture II detects HPV DNA by using two probe sets that distinguish HPV types by risk level. One set targets high-risk HPV types that are associated with cervical cancer, and the other targets low-risk HPV types that are linked to benign lesions. A positive result can indicate the presence of either high‑risk HPV, low‑risk HPV, or both, depending on which probes produce a signal. It does not test for other sexually transmitted bacteria like Chlamydia trachomatis or Neisseria gonorrhoeae, so the correct grouping is the presence of both high-risk and low-risk HPV types.

Hybrid Capture II detects HPV DNA by using two probe sets that distinguish HPV types by risk level. One set targets high-risk HPV types that are associated with cervical cancer, and the other targets low-risk HPV types that are linked to benign lesions. A positive result can indicate the presence of either high‑risk HPV, low‑risk HPV, or both, depending on which probes produce a signal. It does not test for other sexually transmitted bacteria like Chlamydia trachomatis or Neisseria gonorrhoeae, so the correct grouping is the presence of both high-risk and low-risk HPV types.